Our collaborative study investigating the relationships between chemical structure, polarity, and miscibility in solvent–water systems has been published in Chemical Communications.
This study integrated complementary analyses of Kamlet–Taft parameters and relative permittivity to elucidate the mechanisms underlying the thermoresponsive hydrophilicity of amines. Together with our collaborators at Lafayette College, we revealed that hydrogen bonding and nanoscale ordering, i.e., molecular-level and mean-field, respectively, underlie amine–water interactions. These amine and water self-association are key drivers of the thermal response, which, in turn, influence the thermomorphic hydrophilicity.
The paper is part of the 2025 ChemComm Pioneering Investigators series, recognizing the innovative and creative work of the featured researchers. Read more about the Pioneering Investigators' profiles here.
